Oxford Nanospore has launched its DNA, RNA, and cDNA sequencing device PromethION 2 Integrated (P2i) into open early access.

DNA sequencing is a process whereby scientists identify the exact sequence of nucleotides, or bases, in a DNA molecule.

Building upon the success of Oxford Nanospore’s P2 Solo, which launched in October 2022, the molecular sensor MedTech said its new all-in-one desk top sequencing device facilitates “real-time basecalling and post run analysis directly within the device” to mitigate dependency on external computing resources.

The self-contained device is capable of delivering up to 290 Gb of data per flow cell from native DNA, RNA or cDNA libraries, and utilises onboard NVIDIA Ampere architecture to deliver the “highest quality raw-read data” in real-time.

The MedTech added that each flow cell would be capable of delivering the “lowest price per GB” for Oxford Nanopore sequencing, providing a “rapid and convenient solution for achieving the coverage required for sequencing larger genomes.”

“With the launch of the P2i, Oxford Nanopore is heralding a new era of sequencing technology, offering a fully integrated, plug-and-play device that opens up unparalleled possibilities in both research and applied markets,” said Oxford Nanospore chief executive Gordon Sanghera. “Following the success of the P2 Solo, we are pleased to be able to offer a fully integrated alternative to those researchers who want the same high-quality nanopore sequencing to work straight out of the box.”

The P2i early access is being run in key global territories including Europe, the US, Canada, Japan and parts of the Middle East and Asia.

Last year Oxford Nanopore and the Mayo Clinic announced a multi-year development partnership with the aim to increase understanding and improve the treatment of cancer and genetic disorders.

The companies said at the time they had identified several areas of development, spanning applications from translational research in human genetics to detection of genetic predisposition to cancer.

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